Service de reanimation de chirurgie cardiaque pediatrique, institut cardiologique Paris-Sud, hopital Jacques-Cartier, avenue du Noyer-Lambert, 91300 Massy, France. iciprea@icip.org<\/p>\n

OBJECTIVE: Anaemia is the main complication following haemodilution in paediatric cardiac surgery. Iron oral therapy is ineffective to improve anaemia. The aim of this study is to assess the effect of a single dose of intravenous iron saccharate Venofer. STUDY DESIGN: Open, randomized. PATIENTS AND METHODS: 93 patients were randomized in two groups. The first one is the control group without iron supplementation and the second one received a 5 mg\/kg injection of Venofer administered at day 1. Three biological factors were studied on day 1 and day 5 following surgery: haemoglobin, ferrritin and reticulocyte rate. Student test was used for statistical analysis of results. RESULTS: Age, weight, haemoglobin, ferritine and reticulocyte on day 1 were similar in both group (no significant difference). On day 5 ferritin was higher in the treated group 215+\/-87 vs 101+\/-55 mug\/l in the non treated group (P<0.001). Reticulocyte rate was also higher in the treated group 3.25+\/-1.16 vs 2.65+\/-0.97% (P<0.005) in the untreated group. CONCLUSION: Postoperative systemic inflammation is probably the factor which impaired the effect of oral iron therapy. Parenteral iron may act by treating a functional iron deficiency and\/or by increasing endogenous erythropoietin synthesis. Faster reversibility of anaemia following iron injection improves quality of the postoperative recovery.<\/div>\n","protected":false},"excerpt":{"rendered":"

Editorial: Ann Fr Anesth Reanim Fecha: 01\/10\/2005 Hulin S, Durandy Y. Acceso al enlace publicador Service de reanimation de chirurgie<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[4],"tags":[],"_links":{"self":[{"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/posts\/112"}],"collection":[{"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/comments?post=112"}],"version-history":[{"count":1,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/posts\/112\/revisions"}],"predecessor-version":[{"id":906,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/posts\/112\/revisions\/906"}],"wp:attachment":[{"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/media?parent=112"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/categories?post=112"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/tags?post=112"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}