{"id":401,"date":"2010-10-01T00:00:01","date_gmt":"2010-10-01T00:00:01","guid":{"rendered":"https:\/\/awge.doctime.es\/?p=401"},"modified":"2016-05-24T08:21:08","modified_gmt":"2016-05-24T06:21:08","slug":"awge-61","status":"publish","type":"post","link":"https:\/\/awge.doctime.es\/index.php\/2010\/10\/01\/awge-61\/","title":{"rendered":"Transfusion thresholds and other strategies for guiding\r\nallogeneic red blood cell transfusion"},"content":{"rendered":"<p>The Cochrane Library<br \/>\nPaul A Carless, David A Henry, Jeffrey L Carson, Paul PC Hebert, Brian McClelland, Katharine Ker<br \/>\n<a href='' target='_blank'>Acceso al enlace publicador<\/a><\/p>\n<p>Background<br \/>\nMost clinical practice guidelines recommend restrictive red cell transfusion practices, with the goal of minimising exposure to allogeneic blood (from an unrelated donor). The purpose of this review is to compare clinical outcomes in patients randomised to restrictive versus liberal transfusion thresholds (triggers).<br \/>\nObjectives<br \/>\nTo examine the evidence for the effect of transfusion thresholds on the use of allogeneic and\/or autologous blood, and the evidence for any effect on clinical outcomes.<br \/>\nSearch strategy<br \/>\nTrials were identified by: computer searches of the Cochrane Central Register of Controlled Trials (the Cochrane Library Issue 3, 2009),<br \/>\nOVID MEDLINE (1966 to August 2009), Current Contents (1993 to November 2004), and the Web of Science (2004 to August<br \/>\n2009). References in identified trials and review articles were checked and experts contacted to identify any additional trials.<br \/>\nSelection criteria<br \/>\nControlled trials in which patients were randomised to an intervention group or to a control group. Trials were included where<br \/>\nintervention groups were assigned on the basis of a clear transfusion \u2019trigger\u2019, described as a haemoglobin (Hb) or haematocrit (Hct)<br \/>\nlevel below which an RBC transfusion was to be administered.<br \/>\nData collection and analysis<br \/>\nRelative risks of requiring allogeneic blood transfusion, transfused blood volumes and other clinical outcomes were pooled across trials,<br \/>\nusing a random effects model. The risk of bias was assessed.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Cochrane Library Paul A Carless, David A Henry, Jeffrey L Carson, Paul PC Hebert, Brian McClelland, Katharine Ker Acceso<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[4],"tags":[],"_links":{"self":[{"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/posts\/401"}],"collection":[{"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/comments?post=401"}],"version-history":[{"count":1,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/posts\/401\/revisions"}],"predecessor-version":[{"id":677,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/posts\/401\/revisions\/677"}],"wp:attachment":[{"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/media?parent=401"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/categories?post=401"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/tags?post=401"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}