﻿{"id":433,"date":"2012-11-01T00:00:01","date_gmt":"2012-11-01T00:00:01","guid":{"rendered":"https:\/\/awge.doctime.es\/?p=433"},"modified":"2016-05-24T08:01:48","modified_gmt":"2016-05-24T06:01:48","slug":"awge-5","status":"publish","type":"post","link":"https:\/\/awge.doctime.es\/index.php\/2012\/11\/01\/awge-5\/","title":{"rendered":"Hepcidin and the Iron-Infection Axis"},"content":{"rendered":"<div class=\"editorialPost\"><strong>Editorial: science<\/strong><\/div>\n<div class=\"fechaPost\">Fecha: 01\/11\/2012<\/div>\n<div class=\"autorPost\">Hal Drakesmith1* and Andrew M. Prentice2*<\/div>\n<div class=\"enlacePost\"><a target=\"_blank\">Acceso al enlace publicador<\/a><\/div>\n<hr \/>\n<div class=\"resumenPost\">Iron lies at the center of a battle for nutritional resource between higher organisms and their microbial<br \/>\npathogens. The iron status of the human host affects the pathogenicity of numerous infections<br \/>\nincluding malaria, HIV-1, and tuberculosis. Hepcidin, an antimicrobial-like peptide hormone, has<br \/>\nemerged as the master regulator of iron metabolism. Hepcidin controls the absorption of dietary iron<br \/>\nand the distribution of iron among cell types in the body, and its synthesis is regulated by both iron and<br \/>\ninnate immunity. We describe how hepcidin integrates signals from diverse physiological inputs,<br \/>\nforming a key molecular bridge between iron trafficking and response to infection.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Editorial: science Fecha: 01\/11\/2012 Hal Drakesmith1* and Andrew M. Prentice2* Acceso al enlace publicador Iron lies at the center of<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/posts\/433"}],"collection":[{"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/comments?post=433"}],"version-history":[{"count":1,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/posts\/433\/revisions"}],"predecessor-version":[{"id":620,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/posts\/433\/revisions\/620"}],"wp:attachment":[{"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/media?parent=433"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/categories?post=433"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/awge.doctime.es\/index.php\/wp-json\/wp\/v2\/tags?post=433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}